Thursday, October 23, 2025

Quantum Echoes shows promise, but bioinformatics remains classical for now

Google announced a major new milestone in quantum computing with the debut of its Quantum Echoes algorithm running on the Willow processor. The company describes the result as a “verifiable quantum advantage,” meaning a quantum computer has solved a problem much faster than a classical supercomputer, and the outcome can be independently checked rather than simply asserted.

In this experiment, Quantum Echoes completed a complex physics simulation roughly 13,000 times faster than one of the world’s top supercomputers. Google made a similar claim back in 2019, but that result was later questioned when better classical algorithms narrowed the gap (https://www.quantamagazine.org/google-and-ibm-clash-over-quantum-supremacy-claim-20191023/). The new finding stands out because it adds verifiability. Another quantum device, or even an experimental analog, can reproduce the result, offering confidence that the computation truly worked as intended.

The Quantum Echoes algorithm explores how information spreads and mixes within a quantum system, a behavior often called the “quantum butterfly effect.” The process evolves a system forward in time, introduces a small disturbance, and then reverses the sequence to see how that disturbance alters the final state. The “echo” that emerges reveals subtle details about the system’s internal dynamics.

A highlight of the study is a molecular ruler experiment conducted with researchers at the University of California, Berkeley. The team used techniques inspired by nuclear magnetic resonance (NMR) to measure molecular distances beyond the reach of existing NMR instruments. This is where the work becomes bioinformatics adjacent. It touches on structural biology and computational chemistry, fields that feed directly into protein modeling, ligand prediction, and understanding molecular function. A quantum algorithm that improves molecular modeling could one day influence drug discovery or biomolecular design.

Google frames the result as a step away from demonstrations of “quantum supremacy,” which mainly prove that quantum computers can outperform classical ones, toward “useful quantum computing,” where the output has practical scientific meaning. The Willow processor is the latest generation of Google’s superconducting-qubit hardware, with lower error rates and better coherence. The company’s roadmap points toward building logical qubits with full error correction, the next milestone for fault-tolerant systems.

For most researchers, including those of us in bioinformatics, quantum computing is still something to watch rather than something to use. It is fascinating work, but not yet part of daily analysis. No one is yet using a quantum processor for RNA-seq or proteomics data in any practical or published workflow. The systems remain experimental, operate under highly controlled conditions, and rely on specialized algorithms that sit far outside the scope of current pipelines.

Even though this study reaches into biologically relevant territory, the path from fundamental quantum experiments to applied computational biology will take time. The field is still in what many call the “noisy intermediate-scale quantum” stage. Devices have dozens or hundreds of qubits, but not enough stability or error correction for routine use. Meaningful biological applications are still years away.

For now, classical high-performance computing and GPU-accelerated workflows continue to drive discovery in genomics, proteomics, and metabolomics. Quantum computing could eventually complement these methods, particularly for quantum chemistry and molecular simulation problems where electronic interactions are difficult to model classically. Making that transition will require robust hardware, lower error rates, and algorithms designed for biological data. From a bioinformatics perspective, this announcement is less about immediate utility and more about setting the stage for those future tools. If the field progresses from verifiable advantage to fault-tolerant systems, quantum computing could become a new dimension of computational biology, with hybrid approaches that combine classical models and quantum subroutines for complex molecular simulations.

It is impressive work, and it hints at what the next decade of computing could look like. But for now, quantum computing remains an observer rather than a participant in bioinformatics. Quantum Echoes shows promise, but bioinformatics remains classical for now.

Sources:

Google Blog: https://blog.google/technology/research/quantum-echoes-willow-verifiable-quantum-advantage/

Quanta Magazine: https://www.quantamagazine.org/google-and-ibm-clash-over-quantum-supremacy-claim-20191023/

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